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. 2023 Nov 25;2:100849. doi: 10.1016/j.gimo.2023.100849

Table 5.

Detection rate of BRCA1/2 PVs in sporadic breast cancer by age group

Age BC Sporadic TNT Other
<30 Number tested 48 61
BRCA1/2 6 2
% 12.50% 3.28%
PALB2 1 1
Combined % 14.5% 4.9%
30-39 Number tested 193 92
BRCA1/2 15 3
% 7.77% 3.26%
PALB2 3 1
Combined % 9.3% 4.3%
40-49 Number tested 137 114
BRCA1/2 11 2
% 8.03% 1.75%
PALB2 1 2
Combined % 8.8% 3.5%
50-59 Number tested 159 237
BRCA1/2 8 5
% 5.03% 2.11%
PALB2 4 0
Combined % 7.5% 2.1%
>60 Number tested 15 237
BRCA1/2 0 1
% 0.00% 0.42%

BC, breast cancer; TNT, triple negative tumor.