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. 2024 Dec 3;19(12):e0314744. doi: 10.1371/journal.pone.0314744

Table 1. Participant characteristics and selected cardiovascular variables at rest.

Variable APOEε4+ APOEε4- P-value
(Effect Size)
n 37 50
Sex (M/F) 13 / 24 14 / 36
Age (y) 63 ± 4 63 ± 4 0.848 (0.042)
Ethnicity
 Hispanic 0 1
 Non-Hispanic 37 49
Race
 African American 1 0
 Asian 0 1
 White 36 49
Education (y) 17 ± 2 17 ± 3 0.507 (0.145)
Height (cm) 171 ± 9 168 ± 8 0.143 (0.321)
Weight (kg) 78 ± 15 76 ± 16 0.553 (0.129)
Body Mass Index (kg/m2) 27 ± 4 27 ± 4 0.854 (0.040)
HR (bpm) 60 ± 9 60 ± 8 0.907 (0.025)
Systolic BP (mmHg) 127 ± 17 125 ± 14 0.599 (0.115)
Diastolic BP (mmHg) 76 ± 8 75 ± 8 0.385 (0.189)
Mean Arterial BP (mmHg) 93 ± 10 92 ± 9 0.457 (0.162)
MoCA 28 ± 2 28 ± 2 0.684 (0.089)
Family History of Dementia (n, %) 26, 70 34, 68
Controlled Hypertension (n, %) 6, 16 12, 24

Values expressed as mean ± SD. APOE, apolipoprotein; BP, blood pressure; HR, heart rate; MoCA, Montreal Cognitive Assessment. P-value indicates result of independent samples t-test comparing APOEε4 positive (APOEε4+) and APOEε4 negative (APOEε4-) adults. Effect size calculated using Cohen’s d.