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. 2024 Nov 20;14:1419923. doi: 10.3389/fonc.2024.1419923

Table 1.

Comparison of characteristics of the main case reports published on GSCC.

Author No. of
patients
Tumor location/kind of
extension
Gastric mucosa involved by
cancer
Adhesion to
criteria of Parks
Immunoistochemistry Squamous metaplasia Intestinal metaplasia Gastric resection
Boswell 12 Yes (2 pts) Yes PAS- (12 pts) Yes (1 pt) Yes 5 (pts)
Danish Kumar 1 Cardia-lesser curvature/exophytic No No CK5/6 +, p63 +
Guangyao Wang 1 Posterior wall/exophytic No Yes CK 5/6 +, p63 +, CKpan and glutathione S transferase π +, (CD)56-, CDX-2-, chromogranin A-, CK20-, CK7-, S100-, Syn-, Villin-, P-glycoprotein-, EGFR-, p53- Yes
Hideyuki Wakabayashi 1 Lesser curvature/exophytic No Yes Yes
Jagoda Jakubik 1 Fundus/endophytic Yes Yes p63 +, CK7 -, CK 19/20 -, CDX2 -, PAS - Yes
Juan Antonio González-Sánchez 1 Esophagus-fundus-lesser curvature/endophytic Yes No CK5+, CK7+, CK20+, TTF1+, p63+, chromogranin+, synaptophysin+ No Yes
Kehua Zhou 1 Fundus-posterior wall/exophytic No Yes p40+, CK5/6+, CK7+, TTF-1-, CK20-, CDX2- No No
Xiao Wang 1 Corpus/wall thickness Yes Yes CK5/6+, p63+, CKL- Yes Yes
Rodrigo De Assis Moraes 1 Antrum-body-corpus Yes Yes AE1/AE3+, CK5/6+, CK7+, p63+ Yes
Shengqiang Gao 1 Antrum-corpus/
wall thickness
No Yes Yes
Sun Hwi Hwang 1 Fundus/exophytic No Yes No Yes
Xu-Dong Wu 1 Posterior wall/exophytic No Yes Yes
Ying Meng 7 4 lesser curvature, 2 greater curvature, 1 diffuse Not well specified Yes No
Yuki Katsura 1 Corpus-posterior wall/
wall thickness
No Yes CK5/6+, p40+ No Yes
Yukinori Yamagata 1 Posterior wall of body/
wall thickness
Yes Yes AE1/AE3+, CK5/6+, CDX2+, CK20+/-, p63-, p40-, CK7-, synaptophysin-, α-fetoprotein- No Yes Yes
Wolf von Waagner 1 Fundus/wall thickness No Yes CK5/6+, p63+, CD117-, CK20-, p16- Yes
Guzman Rojas 1 Corpus-lesser curvature/
Endophytic
Yes Yes CK5/6+, p63+, CK7-, CK20- Yes
Segura 1 Fundus/wall thickness Yes Yes p63+ No Yes No
Hara 1 Greater curvature/exophytic No Yes Yes
Tokuhara 1 Lesser curvature/
wall thickness
Yes Yes Yes
Vailas 1 Fundus/wall thickness Yes Not specified AE1/AE3+, p40+, Chromogranin A−, Synaptophysin−, c-erB-2/HER2−CK14+,
p53+, CK 5/6+, p63+, MUC1+, PAS-
Yes
Gülçiçek 1 Antrum-posterior wall/
wall thickness
Yes Yes p63+, CK 5/6+ and CK7+ Yes Yes
Yang Chen 21 7 body, 6 fundus, 7 cardias, 1 antrum Not well specified No
(6 pts)
p63+, CK 5/6+ (4 pts) Yes
(15 pts)
Yeon Soo Chang 1 Anastomotic site/
wall thickness
No Yes p63+, CK 5/6+, CK7-, CK20- Yes
Callacondo-Riva 1 Antrum/wall thickness No Yes p63+, CK 5/6+, No Yes Yes
Choi 1 Greater curvature/
wall thickness
Not well specified Yes Yes Yes
Marubashi 1 Lesser curvature-posterior wall-antrum/wall thickness Not well specified Yes CK 5/6+, CK8+, CK17+, CK19+ No Yes
Schwab 1 Anterior and posterior walls lesser curvature/
wall thickness
No Yes No Yes
Karaka 1 Lesser curvature/
wall thickness
Not well specified Yes Yes
Won Lee 2 Antrum-body Yes Yes p53+, p16 - No Yes
(2 pts)
Lei Gao 1 Antrum/exophytic No Yes p63+, CK 5/6+, CD117- Yes
Little 1 Antrum/exophitic No Yes AE1/AE3+, CK5+, p63+ Yes
Mardi 1 Antrum/wall thickness No Yes CK5/6+, CK10+, CK19+, CK14+, CK7-, CK20- Yes
Modi 1 Lesser curvature/
Endophytic
Yes Yes Yes
Oono 1 Cardias Yes No Yes Yes (ESD)
Patnayak 1 Antrum/wall thickness Yes Yes No Yes
Raju 1 Posterior wall/
wall thickness
Not well specified Yes No
Yildirim 1 Antrum/exophytic Not well specified Yes No Yes
Dursun 1 Corpus/antrum/lesser curvature/wall thickness Yes Yes No
Takita 1 Cardia/Lesser curvature Yes No p53- Yes Yes
Our case 1 Posterior wall/
Exophytic
No Yes AE1/AE3 +, CK5/6+, CK7 +, CK8+, p40+, p63+, CK19+, CDX2+, CK20 -, PAS-, CD 45 (LCA) -, TTF-1 -, ERG-, S100 -, smooth muscle actin - No No

Pts, patients; ESD, endoscopic submucosal dissection.