. 2024 Dec 3;14:30109. doi: 10.1038/s41598-024-81934-6

Table 3.

Associations between initial peritoneal dialysis prescription at start and patient-reported outcomes.

Outcome	PD Volume	QoL score, mean ± SD	Score difference (95% CI), PD volume ≤ 4 L/day (N pts = 98) vs. > 4 L/day (N pts = 244)
Outcome	PD Volume	QoL score, mean ± SD	Model 1^a	Model 2^b	Model 3^c	Model 4^d	Model 5^e	Model PS^f
PCS	> 4 L/day	43.9 ± 8.5	ref	ref	ref	ref	ref	ref
	≤ 4 L/day	43.3 ± 8.9	-0.68 (-3.07,1.71)	-0.21 (-2.62,2.20)	-0.56 (-2.89,1.78)	-0.38 (-2.81,2.06)	-0.18 (-2.56,2.21)	-0.35 (-2.93,2.23)
MCS	> 4 L/day	46.6 ± 11.4	ref	ref	ref	ref	ref	ref
	≤ 4 L/day	45.7 ± 10.3	-0.31 (-3.30,2.67)	0.00 (-3.07,3.06)	-0.28 (-3.37,2.81)	-0.26 (-3.47,2.94)	-0.21 (-3.44,3.01)	-0.50 (-3.74,2.75)

Outcome	PD Volume	Outcome, %	Odds ratio (95% CI), PD volume ≤ 4 L/day vs. > 4 L/day
CESD 10 +	> 4 L/day	41%	ref	ref	ref	ref	ref	ref
	≤ 4 L/day	39%	0.81 (0.47,1.40)	0.87 (0.49,1.53)	0.97 (0.54,1.76)	0.90 (0.49,1.67)	0.90 (0.49,1.67)	0.93 (0.51,1.69)

Outcome

PD Volume

Outcome, %

Odds ratio (95% CI), PD volume ≤ 4 L/day vs. > 4 L/day

Model 1^a

Model 2^b

Model 3^c

Model 4^d

Model 5^e

Model PS^f

CESD 10 +

> 4 L/day

41%

ref

≤ 4 L/day

39%

0.81

(0.47,1.40)

0.87

(0.49,1.53)

0.97

(0.54,1.76)

0.90

(0.49,1.67)

0.90

(0.49,1.67)

0.93

(0.51,1.69)

PD: peritoneal dialysis, HD: hemodialysis, CAPD: continuous ambulatory peritoneal dialysis, APD: automated peritoneal dialysis, eGFR: estimated glomerular filtration rate, BMI: body mass index, N pts: number of patients

a. adjusted for PD modality (CAPD/APD);

b. Model 1 + adjusted for age, sex, BMI

c. Model 2 + Charlson comorbidity index, albumin, potassium, hemoglobin

d. Model 3 + eGFR

e. Model 4 + icodextrin, assisted PD

f. Stratified by PD modality (CAPD/APD); adjusted for propensity score only