REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit monoclonal anti-LRRK2	Abcam	ab-133474
Rabbit monoclonal anti-phosphorylated LRRK2	Abcam	ab-133450
Mouse monoclonal anti-iNOS	Santa Cruz Biotechnology	sc-7271
Mouse monoclonal anti-COX2	Santa Cruz Biotechnology	sc-376861
Rabbit polyclonal anti- α-synuclein	Santa Cruz Biotechnology	sc-7011
Rabbit polyclonal anti-PGP9.5	Elabscience	E-AB-53097
Rabbit polyclonal anti-NSE	Invitrogen	PA5-94940
Rabbit polyclonal anti-p62	Abcam	ab91526
Mouse monoclonal anti-LAMP2	Invitrogen	MA1-205
Rabbit monoclonal anti-RAB12(phosphor S106)	Abcam	ab256487
Rabbit polyclonal anti-RAB12	Proteintech	18843-1-AP
Rabbit monoclonal anti-RAB10(phosphor T73)	Abcam	ab230261
Mouse monoclonal anti-RAB10	Abcam	ab104859
Mouse monoclonal anti-Occludin	Santa Cruz Biotechnology	sc-133256
Mouse monoclonal anti-ZO-1	Santa Cruz Biotechnology	sc-33725
Mouse monoclonal anti-β-actin	Santa Cruz Biotechnology	sc-47778
Chemicals, peptides, and recombinant proteins
PF06447475	MedChemExpress LLC	HY-12477
Precision Plus protein unstained Standards	Bio-Rad	64333538
Critical commercial assays
Mouse IL-1β ELISA Kit	Abcam	ab197742
Mouse ATP ELISA kit	MyBiosource	MBS267352
Experimental models: Cell lines
SH-SY5Y	ATCC®	CRL-2266™
Experimental models: Organisms/strains
Mouse CD1	Envigo/Inotiv
Software and algorithms
ImageJ	Fiji	Version 1.53
GraphPad 9.0	Prism	Version 8.4