Table 3.
Summary of clinical responses to adoptive T cell therapy
| Total | Virological/Disease Response | Remained Virus/ Disease Free | No Response | Unknown | |
|---|---|---|---|---|---|
| HSCT | |||||
| Paediatric | |||||
| Adenovirus | 6 | 5 | - | 1 | - |
| Cytomegalovirus | 9 | 6 | 1 | 2 | - |
| Epstein–Barr virus | 2 | 2 | - | - | - |
| Polyomavirus (BKV/JCV) | 3 | 1 | - | 2 | - |
| Multiple Viruses | 3 | 2 | 1 | - | - |
| Adult | |||||
| Cytomegalovirus | 14 | 6 | 2 | 6 | - |
| Epstein–Barr virus | 4 | - | 1 | 3 | - |
| Polyomavirus (BKV/JCV) | 4 | 4 | - | - | - |
| Multiple Viruses | 5 | 4 | - | 1 | - |
| SOT | |||||
| Paediatric | |||||
| Cytomegalovirus | 1 | 1 | - | - | - |
| Epstein–Barr virus | 4 | 3 | 1 | - | - |
| Adult | |||||
| Cytomegalovirus | 5 | 4 | - | - | 1 |
| Epstein–Barr virus | 3 | 2 | - | 1 | - |
| Polyomavirus (BKV/JCV) | 4 | 3 | - | 1 | - |
| No Transplant | |||||
| Paediatric | |||||
| Adenovirus | 1 | - | - | 1 | - |
| Epstein–Barr virus | 2 | - | 1 | 1 | - |
| Adult | |||||
| Cytomegalovirus | 2 | - | - | 2 | - |
| Epstein–Barr virus | 3 | 1 | - | 2 | - |
| Polyomavirus (BKV/JCV) | 3 | 2 | - | 1 | - |
| Total | 78 | 46 | 7* | 24 | 1 |
*These patients were at high risk of either recurrent viral reactivation or end organ disease.