Table 3.
Twelve-month adverse events of minocycline for RP patients
| Events | All patients (N = 35) |
|---|---|
| Adverse eventsa | 22 (62.9) |
| Severe adverse events | 0 |
| General | 8 (22.9) |
| Fatigue | 3 (8.6) |
| Memory Loss | 4 (11.4) |
| Tinnitus | 1 (2.9) |
| Weight Gain | 1 (2.9) |
| Dermatologic symptoms | 17 (48.6) |
| Pruritus | 10 (28.6) |
| Skin acne | 3 (8.6) |
| Hyperpigmentation | 11 (31.4) |
| Photosensitivity | 1 (2.9) |
| Gastrointestinal symptoms | 10 (28.6) |
| Nausea | 4 (11.4) |
| Vomiting | 2 (5.7) |
| Abdominal pain | 1 (2.9) |
| Abdominal distension | 2 (5.7) |
| Constipation | 2 (5.7) |
| Diarrhea | 3 (8.6) |
| Neurologic symptoms | 6(17.1) |
| Dizziness | 6 (17.1) |
| Headache | 1 (2.9) |
| Infections | 3 (8.6) |
| Vaginitis | 3 (8.6) |
Values are reported as No. (%)
aMultiple adverse events may occur in the same participant. All events were resolved during the study period without requiring extra medication