Table 1.
Participant Characteristics (N = 58).
| Mean Age (SD) years | 70 (9) |
|---|---|
| # Female | 21 (36 %) |
| Race | |
| White | 37 (64 %) |
| Black | 16 (28 %) |
| Asian | 3 (5 %) |
| Ethnicity | |
| Hispanic or Latino | 4 (7 %) |
| Education | |
| High School or G.E.D | 10 (17 %) |
| Some College or Associate's Degree | 7 (12 %) |
| Bachelor’s Degree | 12 (21 %) |
| Graduate or Professional Degree | 29 (50 %) |
| Vascular Risk Factors | |
| Hypertension | 47 (81 %) |
| Hyperlipidemia | 31 (53 %) |
| Diabetes Mellitus Type 2 | 22 (38 %) |
| Atrial Fibrillation | 17 (29 %) |
| Obstructive Sleep Apnea | 10 (17 %) |
| Coronary Artery Disease | 8 (14 %) |
| Cardiomyopathy | 5 (9 %) |
| Index Ischemic Event | |
| Stroke | 55 (95 %) |
| Central Retinal Artery Occlusion | 1 (2 %) |
| Transient Ischemic Attack | 2 (3 %) |
| Median Days Since Event (IQR) | 203 (102) |
| Index Stroke Location | |
| Cortical | 28 (48 %) |
| Subcortical | 24 (41 %) |
| Cerebellar | 6 (10 %) |
| Index Event TOAST Criteria | |
| Small Vessel Occlusion | 16 (28 %) |
| Large Artery Atherosclerosis (8 ICAD, 2 ECAD) | 10 (17 %) |
| Cardioembolic (10 Afib, 1 CMY, 1 myxoma) | 12 (21 %) |
| Cryptogenic (14 ESUS) | 15 (26 %) |
| Other Known Cause (1 Dissection, 1 periprocedural) | 2 (3 %) |
| Baseline Imaging Findings | |
| Median WMH Volume mL (IQR) | 13.9 (13.7) |
| Mean Brain Parenchymal Fraction (SD) | 68.5 % (3.7) |
| Presence of Lacunes | 27 (47 %) |
| Presence of Cortical Infarcts | 23 (40 %) |
| Presence of Cerebral Microbleeds | 18 (31 %) |
Afib = atrial fibrillation; CMY = cardiomyopathy; ECAD = extracranial atherosclerotic disease; ESUS = embolic stroke of unknown source; ICAD = intracranial atherosclerotic disease; SD = standard deviation; IQR = interquartile range; TOAST = Trial of ORG 10172 in Acute Stroke Treatment (Adams et al., 1993); WMH = white matter hyperintensity.