Table 1.
Features required for diagnosis of GBS | |
Progressive weakness in legs and arms (sometimes initially only in legs) | |
Areflexia (or decreased tendon reflexes) in weak limbs |
Acute inflammatory demyelinating polyneuropathy (AIDP) | |
---|---|
Additional symptoms | Nerve conduction study findings |
Progressive phase lasts days to 4 weeks | Features of demyelination (only assessable if distal CMAP amplitude is > 10% LLN) |
Relative symmetry of symptoms | Prolonged distal motor latency |
Mild sensory symptoms or signs | Decreased motor nerve conduction velocity |
Cranial nerve involvement, especially bilateral weakness of facial muscles | Increased F‐wave latency, conduction blocks and temporal dispersion |
Autonomic dysfunction | |
Pain (often) |
Acute motor axonal neuropathy (AMAN) | |
---|---|
Additional symptoms | Nerve conduction study findings |
Progressive phase lasts days to 4 weeks | No features of demyelination (or, one demyelinating feature in one nerve if distal CMAP amplitude is < 10% LLN) |
Relative symmetry of symptoms | Distal CMAP amplitude is < 80% LLN in at least two nerves |
No sensory symptoms or signs | Transient motor nerve conduction block may be present (possibly caused by antiganglioside antibodies) |
Cranial nerve involvement (rarely) | No features of demyelination (or, one demyelinating feature in one nerve if distal CMAP amplitude is < 10% LLN) |
Autonomic dysfunction | — |
Pain (sometimes) | — |