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. 2024 Dec 4;4(12):3067–3083. doi: 10.1158/2767-9764.CRC-24-0310

Figure 1.

Figure 1

Untargeted analysis of CD45+ immune cells in patients with MDS, AML, and CMML by CyTOF. A, Multidimensional scale plot depicting the relationship between BM samples of patients with LR-MDS (n = 12), HR-MDS (n = 15), AML (n = 16), and CMML (n = 5). B, Heatmap showing the expression of the markers used for the characterization of each cell cluster. C, UMAP displaying the major immune cell clusters. D, Box charts displaying the frequency of each cell cluster. E, Violin plots showing the expression level of CXCR3 in the CD8 T1, CD8 T2, and CD4 T2 clusters, respectively. Kruskal–Wallis followed by the “two-stage” Benjamini, Krieger, and Yekutieli multiple comparison test was used in D. One-way ANOVA followed by the “two-stage” Benjamini, Krieger, and Yekutieli multiple comparison test was used in E. *, P < 0.05; **, P < 0.01.