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. 2024 Dec 4;19(12):e0314502. doi: 10.1371/journal.pone.0314502

Table 1. Number of associated rare variants with different range of weighted MAF by region in the haplotype pool.

Across all simulated data sets, most of the variants with weighted MAF less than 0.0001 were those non-polymorphic, singleton, doubletons, or triptons.

Region (0, 0.0001) [0.0001, 0.001) [0.001, 0.01) [0.01, 0.05)
1 204 4 3 1
2 172 2 0 0
3 204 3 2 0
4 220 5 0 0
5 197 2 1 0
6 185 6 1 0
Total 1182 22 7 1