Table 8.

Summary of side effects and contraindications

Parameter	Abrocitinib
Common side effects	Herpes simplex, headaches, nausea, nasopharyngitis, elevated blood creatinine phosphokinase
Serious side effects	MACE, thrombosis, serious infections, cancer
Laboratory abnormalities	Lymphopenia, thrombocytopenia, elevated lipid parameters
Risk factors	Smoking, cardiovascular history
Monitoring requirements	CBC and lipid profile after 4 weeks
Contraindications	Active infections, significant hepatic impairment, pregnancy, breastfeeding, hypersensitivity