Table 1.
Summary of key primary and secondary outcomes.
| Outcome | Number of studies | Number of participants | SMD (95%CI) | I2 | p value for overall effect | p value for comparison |
|---|---|---|---|---|---|---|
| Red blood cell transfusion (all) | 9 | 424 | ‐0.16 (‐0.29 to ‐0.20) | 0% | 0.02 | 0.04 |
| TEG | 5 | 281 | ‐0.05 (‐0.22 to 0.11) | 0% | 0.54 | |
| ROTEM | 5 | 143 | ‐0.36 (‐0.59 to ‐0.13) | 0% | 0.002 | |
| Platelet transfusion (all) | 7 | 263 | ‐0.33 (‐0.56 to ‐0.10) | 41% | 0.004 | 0.02 |
| TEG | 4 | 146 | ‐0.52 (‐0.75 to ‐0.28) | 0% | < 0.001 | |
| ROTEM | 3 | 117 | ‐0.10 (‐0.36 to 0.16) | 0% | 0.44 | |
| Fresh frozen plasma transfusion (all) | 8 | 299 | ‐0.64 (‐1.01 to ‐0.28) | 78% | < 0.001 | 0.88 |
| TEG | 4 | 146 | ‐0.63 (‐0.90 to ‐0.35) | 21% | < 0.001 | |
| ROTEM | 4 | 153 | ‐0.61 (‐0.13 to 0.11) | 89% | 0.10 | |
| Blood loss (all) | 6 | 316 | ‐0.28 (‐0.43 to ‐0.12) | 0% | < 0.001 | 0.56 |
| TEG | 5 | 280 | ‐0.26 (‐0.43 to ‐0.09) | 0% | < 0.002 | |
| ROTEM | 1 | 36 | ‐0.41 (‐0.87 to 0.06) | ‐ | 0.09 | |
| ICU duration of stay (all) | 5 | 275 | ‐0.18 (‐0.36 to ‐0.01) | 0% | 0.04 | 0.58 |
| TEG | 4 | 225 | ‐0.21 (‐0.40 to ‐0.01) | 0% | 0.04 | |
| ROTEM | 1 | 50 | ‐0.08 (‐0.48 to 0.31) | 0.68 |
SMD, standardised mean difference; TEG, thromboelastography; ROTEM, rotational thromboelastometry.