Table 2.
P-values derived from two- and three-way ANOVA interaction tests of study 2 phenotypic data
| Parameter | Strain | Diet | Strain: Diet | Week | Strain: Week | Diet: Week | Strain: Diet: Week |
|---|---|---|---|---|---|---|---|
| % Change Body Weight | 1.1E-45 | 2.9E-16 | 1.5E-04 | 3.6E-34 | 2.8E-11 | 4.3E-03 | 1.7E-01 |
| Triglycerides | 4.7E-24 | 3.5E-01 | 9.8E-03 | 4.0E-05 | 1.1E-02 | 1.7E-01 | 1.7E-01 |
| Insulin | 3.6E-07 | 3.5E-01 | 2.0E-01 | 2.6E-04 | 6.1E-05 | 1.7E-01 | 1.7E-01 |
| Glucose | 2.0E-13 | 3.5E-01 | 2.1E-02 | 5.1E-16 | 5.3E-03 | 1.7E-01 | 1.7E-01 |
| MRI-Total Fat | 2.9E-11 | 4.1E-01 | 5.6E-01 | – | – | – | – |
| FDG-PET-VAT | 1.3E-12 | 3.4E-01 | 9.6E-01 | – | – | – | – |
| FDG-PET-Quad | 1.4E-02 | 5.7E-01 | 5.6E-01 | – | – | – | – |
| FDG-PET-BAT | 1.3E-02 | 5.7E-01 | 5.6E-01 | – | – | – | – |
| VAT Wt/BW | 4.5E-09 | 2.1E-01 | 5.6E-01 | – | – | – | – |
| SAT Wt/BW | 3.0E-04 | 4.4E-01 | 7.6E-01 | – | – | – | – |
| BAT Wt/BW | 1.3E-16 | 1.9E-02 | 7.6E-01 | – | – | – | – |
| Liver Wt/BW | 1.7E-07 | 8.3E-01 | 7.3E-01 | – | – | – | – |
| Quad Wt/BW | 1.6E-11 | 4.0E-01 | 7.8E-01 | – | – | – | – |
| Gastro Wt/BW | 6.2E-19 | 1.3E-01 | 6.2E-01 | – | – | – | – |
| Pancr Wt/BW | 2.1E-03 | 6.8E-01 | 7.9E-01 | – | – | – | – |
| Brain Wt/BW | 9.5E-08 | 5.2E-01 | 7.6E-01 | – | – | – | – |
BAT, brown adipose tissue; FDG-PET, 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography; gastro, gastrocnemius muscle; MRI, magnetic resonance imaging; Pancr, pancreas; Quad, quadriceps muscle; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; Wt, weight.