Table 1.
Characteristicsa of the analytic cohorts.
| Characteristic | Men |
Women |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| ARIC N = 5897 | PLCO N = 71,667 | NIH-AARP N = 187,528 | EPIC N = 47,040 | ARIC N = 7566 | PLCO N = 74,087 | NIH-AARP N = 126,906 | EPIC N = 108,486 | WHI N = 91,033 | |
| Agea, years, mean (SD) | 57.0 (6.0) | 63.0 (5.0) | 62.0 (5.3) | 60.0 (8.0) | 57.0 (6.0) | 63.0 (5.0) | 62.0 (5.0) | 57.0 (10.0) | 64.0 (7.0) |
| Heighta, meters, mean (SD) | 1.76 (0.07) | 1.78 (0.08) | 1.78 (0.07) | 1.76 (0.07) | 1.62 (0.06) | 1.63 (0.02) | 1.63 (0.06) | 1.64 (0.06) | 1.62 (0.07) |
| BMIa, kg/m2 mean (SD) | 27.7 (4.3) | 27.5 (4.2) | 27.2 (4.2) | 26.3 (3.5) | 28.2 (6.1) | 27.1 (5.5) | 26.8 (5.8) | 25.3 (4.2) | 27.2 (5.8) |
| Ethnicity, n (%) | |||||||||
| White | 4707 (80) | 63,452 (89) | 176,095 (95) | NA | 5475 (72) | 65,856 (89) | 116,400 (93) | NA | 76,213 (84) |
| Black | 1190 (20) | 3163 (4) | 3961 (2) | 2091 (28) | 4076 (6) | 5582 (5) | 10,287 (11) | ||
| Other | NA | 5012 (7) | 5670 (3) | NA | 4129 (6) | 3443 (3) | 4281 (5) | ||
| Missing | 0 (0) | 40 (0) | 0 (0) | 0 (0) | 26 (0) | 0 (0) | 252 (0) | ||
| Smoking, n (%) | |||||||||
| Ever | 4349 (74) | 45,514 (64) | 125,537 (69) | 31,224 (67) | 3745 (50) | 32,856 (44) | 67,396 (55) | 50,190 (50) | 44,146 (49) |
| Never | 1533 (26) | 26,141 (37) | 55,489 (31) | 15,357 (33) | 3810 (50) | 41,226 (56) | 55,789 (45) | 50,293 (50) | 42,927 (47) |
| Missing | 15 (0) | 12 (0) | 6502 (3) | 459 (1) | 11 (0) | 5 (0) | 3721 (3) | 8003 (7) | 1219 (1) |
| Alcohol consumption, units of alcohol per weeka | 4 (9) | 9 (26) | 8 (20) | 15 (19) | 1 (4) | 9 (26) | 3 (8) | 7 (9) | 2 (5) |
| Missing | 20 (0) | 16,463 (22) | 0 (0) | 20,688 (43) | 11 (0) | 16,463 (22) | 0 (0) | 31,496 (29) | 47 (0) |
| HRT, n (%) | |||||||||
| Ever | 4109 (54) | 49,058 (67) | 77,513 (62) | 25,884 (28) | 54,296 (60) | ||||
| Never | 2242 (35) | 24,578 (33) | 47,797 (38) | 66,873 (72) | 36,659 (40) | ||||
| Missing | 1215 (16) | 356 (0) | 1596 (1) | 15,729 (14) | 78 (0) | ||||
Values in parentheses are percentages unless otherwise stated.
Abbreviations: N, number of participants; BMI, body mass index; HRT, hormone replacement therapy; US, United States; UK, United Kingdom; EPIC, European Prospective Investigation into Cancer and Nutritionb; NIH-AARP, Diet and Health Study; PLCO, Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial; WHI, Women's Health Initiative; ARIC, Atherosclerosis Risk in Communities study; NA, not applicable.
a
These values are based on the index date.
b
Denmark, France, Germany, Italy, the Netherlands, Norway, Spain, Sweden and the United Kingdom.