Table 4.
Antimicrobial activity of melittin, chloramphenicol and melittin-chloramphenicol.
| Strains | Mel (μg/ml) | Chl (μg/ml) | Mel-Chl (μg/ml) | FICi | Interpretation | |||
|---|---|---|---|---|---|---|---|---|
| MIC | MBC | MIC | MBC | MIC | MBC | Mel-Chl | ||
| 6F | 4 | 8 | 128 | >128 | 2–64 | 4–128 | 1 | Addition |
| 11F | 8 | 8 | 64 | >128 | 8–64 | 8–128 | 2 | Indifference |
| 17F | 2 | 4 | 64 | >128 | 2–64 | 4–128 | 2 | Indifference |
| 21F | 8 | 8 | 64 | >128 | 8–64 | 8–64 | 2 | Indifference |
| 29F | 16 | >16 | 128 | >128 | 8–64 | 8–64 | 1 | Addition |
| 33F | 2 | 4 | 16 | 64 | 2–16 | 2–16 | 2 | Indifference |
| 35F | 2 | 4 | 16 | 64 | 2–16 | 2–16 | 2 | Indifference |
| 40F | 4 | 8 | 8 | 32 | 4–8 | 8–8 | 2 | Indifference |
| P1 | 8 | 16 | 16 | 64 | 8–16 | 8–16 | 2 | Indifference |
| P7 | 16 | >16 | 128 | >128 | 8–64 | 8–64 | 1 | Addition |
| P9 | 4 | 8 | 64 | >128 | 2–32 | 2–32 | 1 | Addition |
| P12 | 2 | 4 | 128 | 128 | 1–64 | 1–64 | 1 | Addition |
| P14 | 2 | 2 | 128 | >128 | 1–64 | 2–128 | 1 | Addition |
| P17 | 4 | 8 | 64 | >128 | 2–32 | 4–64 | 1 | Addition |
| P29SH | 8 | 16 | 16 | 32 | 4–8 | 8–16 | 1 | Addition |
| ATCC | 16 | >16 | 32 | 128 | 8–16 | 8–16 | 1 | Addition |
Mel, melittin; Chl, chloramphenicol; FICi, fractional inhibitory concentration indices; MIC and MBC for melittin and rifampicin in combined form.