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. 2024 Nov 21;16:1471698. doi: 10.3389/fnagi.2024.1471698

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Copyright © 2024 Qi, Lian, Guo, He, Li, Li, Luo, Zhang, Huang, Liu, Zheng, Guan, Zhang, Yue, Liu, Zhang, Meng, Wang, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparisons of planar gaze trajectories in different eye movement paradigms among NC, AD-MCI, and AD-D groups. NC group exhibited regular and smooth eye movement trajectories; AD-MCI group demonstrated mild trajectory disorder, manifested as unstable and uncoordinated eye movements; AD-D group displayed highly erratic trajectories, with unstable fixations across all tasks. NC, normal control; AD-MCI, mild cognitive impairment due to Alzheimer’s disease; AD-D, dementia due to Alzheimer’s disease.