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. 2024 Oct 15;123(22):3977–3996. doi: 10.1016/j.bpj.2024.10.009

Figure 6.

Figure 6

Free-energy along the MFEPs for the pathways linking the fused and unfused dNT states shown in Fig. 5. Data are shown for (dashed) σ=0.129κ/d2 and (solid) σ=0.387κ/d2, and free energies are given relative to that of a dNT, Fdt. Colors correspond to different steps, and are chosen to match those in Figs. 3 and 5. Membrane configurations are shown at key steps for σ=0.387κ/d2. Barriers are calculated similarly to Fig. 1.