Fig. 6.

The effects of LHN^TMZ, LHN^rutin and LHN^TMZ+rutin on GB tumor in pathological examination (A) IHC staining of PHH3 indicates the mitotic and proliferation capacity (staining areas are shown with red arrows). (B) IHC staining of CD31 shows the intratumoral microvessel density (staining areas are shown with yellow circles). (C) TEM images of GB tumor cells focusing on the structure of mitochondria (red arrows). (D) Immunoblotting of PARP protein expression in GB tumors. All values were expressed as the biological replicates' mean± SD. *P < 0.05, **P < 0.0001.