Table 3.
Association of AD biomarkers with gender.
| Biomarkers | Male, mean (SD) (n = 38) | Female, mean (SD) (n = 47) | β1* (95% CI) | p-value |
|---|---|---|---|---|
| Aβ42 | 3.6 (2) | 4.1 (2) | 0.15 (−1, 1) | 0.80 |
| Aβ40 | 63.9 (45) | 83.1 (54) | 8.3 (−20, 36) | 0.56 |
| Aβ42/40 | 0.07 (0.04) | 0.07 (0.3) | 0.003 (−0.02, 0.02) | 0.80 |
| p-tau 181 | 2.5 (2) | 2.8 (2) | −0.06 (−1, 1) | 0.91 |
| p-tau 217 | 0.46 (0.5) | 0.33 (0.3) | −0.06 (−0.3, 0.2) | 0.62 |
| Nfl | 56.0 (45) | 46.7 (33) | −16.0 (−37, 5) | 0.14 |
| GFAP | 173.4 (110) | 231.9 (139) | 45.8 (−22, 114) | 0.18 |
| TNFa | 0.54 (0.3) | 0.65 (0.3) | 0.12 (−0.03, 0.3) | 0.12 |
| IL-1B | 0.014 (0.02) | 0.010 (0.01) | −0.003 (−0.01, 0.004) | 0.38 |
| IL-10 | 0.24 (0.3) | 0.36 (0.4) | 0.10 (−0.09, 0.3) | 0.31 |
*β1 represents the average magnitude in which the biomarker differs for females compared to *Model adjusted for age and education.