Table 2. Recipient characteristics and outcomes.
| Characteristics | Recipients by donor type and preservation strategy | |||
|---|---|---|---|---|
| DCD-NMP (n=44) | BD-HMP (n=38) | BD-SCS (n=78) | P value | |
| Sex (M:F) | 37:7 | 29:9 | 60:18 | 0.2 |
| Age (years), mean ± SD | 52±11 | 51±15 | 51±14 | 0.09 |
| Height (cm), mean ± SD | 174±11 | 173±10 | 173±10 | 0.9 |
| Weight (kg), mean ± SD | 82±18 | 83±19 | 83±17 | >0.9 |
| Aeitiology of heart failure, n [%] | – | |||
| Dilated cardiomyopathy | 25 [57] | 18 [47] | 34 [44] | |
| Ischemic cardiomyopathy | 9 [20] | 9 [24] | 21 [27] | |
| Congenital | 2 [5] | 2 [5] | 5 [6] | |
| Viral myocarditis | 2 [5] | 1 [3] | 1 [1] | |
| Restrictive cardiomyopathy | 6 [14] | 0 [0] | 8 [10] | |
| Other | 0 [0] | 8 [21] | 9 [12] | |
| Mechanical support pre-transplant, n [%] | – | |||
| LVAD | 13 [30] | 16 [42] | 21 [27] | |
| VA ECMO | 2 [5] | 1 [3] | 0 [0] | |
| Impella | 2 [5] | 0 [0] | 0 [0] | |
| Redo sternotomy at time of transplant, n [%] | 17 [39] | 25 [66]†,‡ | 28 [36] | 0.0075 |
| Bypass time (min), median (IQR) | 145 (116–175) | 189 (139–233)†,‡ | 150 (119–183) | 0.0015 |
| Cross clamp time (min), median (IQR) | 82 (72–90) | 98 (83–111)†,‡ | 86 (74–100) | 0.0014 |
| Intensive care unit LOS (days), median (IQR) | 6 (3–10) | 5 (3–9) | 4 (3–9) | 0.7 |
| Hospital LOS (days), median (IQR) | 26 (13–42) | 34 (16–58) | 22 (13–39) | 0.2 |
| Permanent stroke, n [%] | 1 [2] | 1 [3] | 1 [1] | 0.8 |
| New renal failure requiring permanent dialysis, n [%] | 0 [0] | 3 [8] | 0 [0] | 0.01 |
| sPGD requiring mechanical support, n [%] | 3 [7] | 2 [5] | 4 [5] | 0.9 |
†, significantly greater than DCD-NMP group on post-hoc analysis; ‡, significantly greater than BD-SCS group on post-hoc analysis. DCD-NMP, donation after circulatory death-normothermic machine perfusion; BD-HMP, brain dead-hypothermic machine perfusion; BD-SCS, brain dead-static cold storage; M, male; F, female; SD, standard deviation; LVAD, left ventricular assist device; VA ECMO, veno-arterial extracorporeal membrane oxygenation; IQR, interquartile range; LOS, length of stay; sPGD, severe primary graft dysfunction.