Table 1.
Patients ‘ characteristics
| Characteristic | All SSc patients |
|---|---|
| Fertility parameters | |
| Age at measurement (years), median (min–max) | 32 (18–40) |
| Number of children, median (min–max) | 0 (0–2) |
| Age at first child (years), median (min–max) | 30 (21–35) |
| Timing of menarche, (years), median (min–max) | 13 (9–20) |
|
Regularity in menstruation Regular cycle (no.[%]) Unregular cycle (no.[%]) Amenorrhea (no.[%]) |
23 (77) 6 (20) 1 (3) |
| Unfulfilled child wish (no.[%]) | 7 (23) |
| Misscarriage (no.[%]) | 3 (10) |
|
Smoking Ongoing (no.[%]) Never (no.[%]) |
2 (7) 28 (93) |
| Disease characteristics | |
| Disease duration (months), median (min–max) | 28 (1–233) |
|
Disease manifestation (no.[%]) dcSSc lcSSc Overlap |
13 (50) 15 (43) 2 (6) |
|
Autoantibody (no.[%]) None Scl70 ACA Other |
6 (20) 17 (57) 5 (17) 4 (6) |
| mRSS, median (min–max) | 7 (0–40) |
| Lung involvement (no.[%]) | 18 (60) |
| Heart involvement (no.[%]) | 2 (7) |
| Treatment at measurement* | |
| Mycophenolate mofetil | 6 (20) |
| Prednisone | 9 (30) |
| Azathioprine | 3 (10) |
| Methotrexate | 8 (27) |
| Sildenafil | 1 (3) |
| Bosentan | 5 (17) |
ACA, anti-centromere antibody, dcSSc, diffuse cutaneous systemic sclerosis; lcSSc, limited cutaneous systemic sclerosis; max, maximum; min, minimum; mRSS, modified Rodnan skin score; no., number; Scl70, anti-topoisomerase II; SSc, systemic sclerosis