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. 2024 Dec 4;15:10566. doi: 10.1038/s41467-024-54780-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a–c Immunglobulin concentrations in the serum of Nmur1^iCre-eGFP Id2^fl/fl and littermate Id2^fl/fl mice were determined by using the LEGENDplex multiplex beads-based assay. a Total immunoglobulin concentration in steady state (Id2^fl/fl n = 8, Nmur1^iCre-eGFP Id2^fl/fl n = 8). b Mice were infected with N. brasiliensis and serum was harvested at d11 post-infection (Id2^fl/fl n = 8, Nmur1^iCre-eGFP Id2^fl/fl n = 9). c Inflammation was induced by intranasal administration of Alternaria alternata (A. alternata) extract. Sera were harvested at d7 after induction of inflammation (Untreated Id2^fl/fl n = 4, A. alternata Id2^fl/fl n = 12, A. alternata Nmur1^iCre-eGFP Id2^fl/fl n = 12). Each symbol represents data from one mouse, mean +/− SD, data are pooled from two (a, b) or three (c) independent experiments. Statistical significance was determined by two-tailed unpaired Mann Whitney test (a–c), *p < 0.05, **p < 0.01. Source data, including exact p-values, are provided as a Source data file Fig. 5.