Figure 1:

Treatment Timeline. Timeline summarizing the treatment course of our patient, including surgery, chemotherapy, radiation therapy, and molecular-targeted therapy. The red box indicates dabrafenib + trametinib; gaps in the red boxes indicate drug holidays. The yellow boxes indicate resistant tumors. PXA: Pleomorphic xanthoastrocytoma, CGA: Comprehensive genetic analysis, Rec: Recurrence, GTR: Gross total resection, TMZ: Temozolomide, Bev: Bevacizumab, LR:Local radiation, CSR: Craniospinal radiation.