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. 2024 Dec 4;7:1617. doi: 10.1038/s42003-024-07289-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 2 — a The UMAP plot shows a comparison of the clustering distribution across HCs as well as herpes zoster patients (HP) and herpes zoster patients (RP) patients. b The bar plot shows the relative contributions of eight subpopulations by samples, including three HAs, three HP patients, and three RP patients. c The box diagram shows the percentages of myeloid, NK and T, and B cells across the three groups. d The heatmap shows the DEGs of B cells among the HAs, herpes zoster patients (HP) and herpes zoster patients (RP) patients. e The heatmap shows the DEGs of MPs among the HAs, herpes zoster patients (HP) and herpes zoster patients (RP) patients. f The heatmap shows the DEGs of neutrophils among the HAs, herpes zoster patients (HP) and herpes zoster patients (RP) patients. g The heatmap shows the DEGs of T cells among the HAs, herpes zoster patients (HP) and herpes zoster patients (RP) patients. h–k Blood routine analysis of the numbers and frequencies of monocytes and lymphocyte from HA and herpes zoster patients. Unpaired t-test were used and the data represent the means ± SEM. ***P < 0. 001, ****P < 0. 0001.