Fig. 2. PEGylation of QDs markedly reduces QD-mediated platelet aggregation. Washed platelets at 2.5 × 108 mL−1 were incubated with either (A) QD-LA (n = 6) and (B) QD-LA-PEG (n = 6), or (D) QD-Pen (n = 8) and (E) QD-Pen-PEG (n = 11) at either 10, 30 or 100 nM in stirring conditions at 37 °C for 10 min whilst aggregation was monitored, with the representative traces shown. Maximal aggregation response after 8 min is shown in (C) and (F). Data is shown as mean ± SD. Statistical significance was calculated using a two-way ANOVA followed by a Sidak's multiple comparison post hoc test. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001.
