Table 2:

Difference between histopathological findings of two groups with granulomatous interstitial nephritis and granulomatous interstitial nephritis with hypercalcemia

	GIN (N = 14)	GIN and Hypercalcemia (N = 6)	P value
No. of glomeruli (mean)	11.4 ± 5.5	12.8 ± 4.1	0.34
Globally sclerosed glomeruli (percentage)	35.1 ± 12.2	9.8 ± 5.6	0.03
Tubulointerstitial fibrosis and atrophy (IFTA)
No IFTA	4 (28.6%)	2 (33.4%)	0.27
Mild (F1)	4 (28.6%)	4 (66.6%)
Moderate (F2)	4 (28.6%)	0
Severe (F3)	2 (14.3%)	0
Interstitial inflammation
No inflammation	4 (28.6%)	2 (33.3%)	0.65
Mild (I1)	3 (21.4%)	3 (50%)
Moderate (I2)	3 (21.4%)	0
Severe (I3)	4 (28.6%)	1 (16.7%)
IF findings	Non-specific C3 deposits	No deposits seen

GIN: Granulomatous interstitial nephritis; F1: 10-25%, F2: 25-50%, F3: >50% interstitial fibrosis and tubular atrophy; I1<25%, I2 25-50%, and I3 > 50% interstitial inflammation; C3: Complement, IF: Immunofluorescence