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. 2024 Oct 28;34(6):589–596. doi: 10.25259/ijn_222_23

Table 3:

Effect of the degree of interstitial fibrosis and tubular atrophy on serum creatinine and proteinuria

No IFTA (n = 6) Mild IFTA (F1) (n = 8) Moderate IFTA (F2) (n = 4) Severe IFTA (F3) (n = 2) P value
Mean serum creatinine at admission (mg/dL) 2.9 ± 1.0 4.8 ± 2.4 6.0 ± 2.7 6.7 ± 1.5 0.09
Mean serum creatinine at 1 month (mg/dL) 2.2 ± 0.9 3.7 ± 1.9 4.2 ± 1.2 5.4 ± 1.1 0.07
Mean serum creatinine at 3 months (mg/dL) 1.3 ± 0.5 2.3 ± 1.4 3.6 ± 1.3 4.2 ± 1.4 0.04
Mean serum creatinine at follow-up (mg/dL) 1.0 ± 0.2 1.7 ± 1.2 3.0 ± 1.8 3.2 ± 1.1 0.01
24-h urine protein at admission (g/day) 2.5 ± 1.1 2.3 ± 0.5 3.2 ± 0.4 3 ± 0.3 0.17
24-h urine protein at follow-up (g/day) 0.7 ± 0.3 1.0 ± 0.5 1.7 ± 0.5 2.1 ± 0.3 0.001

IFTA: Interstitial fibrosis and tubular atrophy