TABLE 2.
Descriptive number (%) of collagen and neurological AESIs within 90 days of follow-up by index antibiotic treatment (without the application of Kaplan–Meier method)
| Index antibiotic treatment | ||
|---|---|---|
| Collagen AESIs, n (%)a | FQ (N = 386,537) | SXT (N = 237,120) |
| Composite | 1,200 (0.31) | 564 (0.24) |
| Tendon rupture | 308 (0.08) | 115 (0.05) |
| Retinal detachment | 173 (0.05) | 96 (0.04) |
| Uveitis | 262 (0.07) | 139 (0.06) |
| Aortic aneurysm | 444 (0.11) | 209 (0.09) |
| Aortic dissection | 25 (0.01) | 14 (0.01) |
a
Some patients experienced both CNS and PNS AEs. AESIs, adverse events of special interest; CNS, central nervous system; PNS, peripheral nervous system; FQ, fluoroquinolone; NTF, nitrofurantoin; SXT, trimethoprim–sulfamethoxazole.