TABLE 3.
EOP of phages ZC01 and ZC03 for selected clinical isolatesa
| P. aeruginosa strain/isolate | Drop test assay | EOP | Source | ||
|---|---|---|---|---|---|
| ZC01 | ZC03 | ZC01 | ZC03 | ||
| PA14b | + | + | 100% | 100% | Reference strain |
| 3845 GSP-3 producer | + | + | 3.4% | 0.02% | HIV patient feces |
| ALERTA 226 (GES-5 carbapenemase-producer) | − | + | nd | 0.06% | Hospital |
| ALERTA 275 (VIM-7 carbapenemase-producer) | − | + | nd | 0.05% | Hospital |
| ALERTA 395 (IMP-18 metallo-beta-lactamase producer) | + | + | 5% | 9% | Hospital |
| Fc79a M | + | + | 2% | 49% | Lung secretion |
| Fc79a PAB NM | + | + | 8% | 51% | Lung secretion |
| Fc7f NM | + | − | 2% | nd | Lung secretion |
| MT222 | + | + | 14% | 0.01% | Tracheal aspirate |
| P13.612 | + | + | 20% | 0.03% | Hospital |
| SC-61 | + | + | 8% | 2% | Nasal secretion |
| H6044c | + | − | 0.6% | nd | Blood |
| H6086c | + | − | 14% | nd | Blood |
| 5757c | + | + | 9.8% | 0.045% | Blood and urine |
a
Clear lysis plaque (+) and no lysis/turbid plaque (−). The EOP value of 100% was considered for the host strain. nd: not determined.
b
Host strain.
c
Isolates analyzed in previous work (46). The full list of the 69 strains evaluated is shown on Table S3.