Table 1.
Clinical basic characteristics and biochemical indexes of participants in three groups
| Parameters | HCs (n = 20) | PNS_In (n = 27) | PNS_Re (n = 17) |
|---|---|---|---|
| Age (Years) | 7.56 (3.4, 13.5) | 5.69 (1.3, 14) | 7.57 (1.7, 12.8) |
| Gender (Male/Female) | 11/9 | 16/11 | 8/9 |
| Mode of birth (Vaginal delivery/ Cesarean delivery) | 15/5 | 21/6 | 14/3 |
| Weight (kg) | 28.25 ± 15.54 | 22.71 ± 10.72 | 27.94 ± 12.67 |
| Breastfeeding time (Month) | 12.300 ± 5.667 | 11.410 ± 5.514* | 6.588 ± 3.842‡‡ |
| Allergic diseases (Yes/NO) | 6/14 | 22/5* ††† | 8/9 |
|
Type of disease (Simple nephropathy/ Nephritis nephropathy) |
- | 19/8 | 10/7 |
| WBC (×106/µL) | - | 10.21 ± 3.934 | 11.43 ± 8.708 |
| NEUT (×106/µL) | - | 4.178 ± 1.938 | 7.020 ± 7.629 |
| PLT (×106/µL) | - | 424.9 ± 156.5 | 402.2 ± 129.8 |
| FIB (g/L) | - | 5.029 ± 0.750 | 5.101 ± 2.365 |
| IgA (g/L) | - | 1.178 ± 0.659 | 1.326 ± 0.858 |
| IgG (g/L) | - | 2.294 ± 1.536 | 2.161 ± 1.992 |
| IgM (g/L) | - | 1.507 ± 0.607 | 1.725 ± 1.144 |
| C3 (g/L) | - | 1.295 ± 0.184 | 1.371 ± 0.578 |
| C4 (g/L) | - | 0.313 ± 0.091 | 0.324 ± 0.148 |
| ALB (g/L) | - | 18.030 ± 2.132 | 19.460 ± 5.397 |
| TC (mmol/L) | - | 8.732 ± 1.574 | 9.008 ± 2.973 |
| TG (mmol/L) | - | 2.459 ± 1.121 | 2.294 ± 1.020 |
| SCr (µmol/L) | - | 33.820 ± 8.625 | 40.280 ± 15.590 |
| 24 h urine protein (mg/kg.d) | - | 161.6 ± 83.84 | 143.1 ± 69.82 |
| MAU (mg/L) | - | 6490.64 ± 6010.21 | 5784.81 ± 11658.76 |
| Proteinuria elimination time (days) | - | 10.00 ± 2.602*** | 20.06 ± 6.240 |
| AST (U/L) | - | 35.89 ± 8.47 | 39.93 ± 31.34 |
| ALT (U/L) | - | 20.24 ± 7.24 | 24.48 ± 12.65 |
proteinuria elimination time (after the first hormone treatment) (*PNS_In VS PNS_Re, *P < 0.05, **P < 0.01, ***P < 0.001; †PNS_In VS HCs, †P < 0.05, ††P < 0.01, †††P < 0.001; ‡PNS_Re VS HCs, ‡P < 0.05, ‡‡P < 0.01)