Table 2.

European Bone and Joint Infection Society (EBJIS) 2021 “Infection Likely” Criteria [15]

European Bone and Joint Infection Society (EBJIS) 2021 Infection Likely Criteria
Periprosthetic joint infection is present when there are two positive findings A + B OR A + C
A Clinical	Clinical Features	• Early radiographic loosening • Wound healing problems • Recurrent fever/ Bacteraemia • Purulence around prosthesis
A Clinical	CRP	• CRP > 10 mg/L
B Laboratory	Synovial fluid	• Leukocyte count > 1500 • PMN > 65%
B Laboratory	Microbiology	• Single Positive Culture (aspiration or intra-operative) • > 1 CFU/mL any organism on sonication
B Laboratory	Histology	• Presence of ≥ 5 neutrophils in a single HPF
C Radiology	Nuclear Imaging	• Positive white cell labelled scintigraphy