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Giant cell tumor of the bone (stage 3). (A) x-ray appearance showing a characteristic purely lytic lesion, destroying the cortex (white arrow) and bulging in the soft tissues; (B) sagittal CT scan shows the aggressive pattern in bone (black asterisk) and soft tissue (white asterisk). (C) Typical histologic features with numerous osteoclast-like giant cells and mononuclear neoplastic cells. (D) high-power histologic appearance.
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