Table 1.
Histopathological criteria | RCM features |
---|---|
Peribulbar and dermal mild inflammatory infiltrate | Round-to-polygonal, mildly refractive cells around the hair bulb at the level of the superficial dermis |
Miniaturized follicles | Reduction of the caliber of the hair shaft in comparison to normal hair as well as reduction of the caliber of the adnexal infundibulum |
Infundibular ostia empty or full of sebum and keratin | Dark infundibula unit (empty) or highly refractive material inside the infundibula (full of sebum and keratin) |
Catagen and telogen germinal units | Catagen: infundibular units connected to the hair shaft Telogen: dilated infundibular unit associated to fibrotic tissue at the level of the superficial dermis Increased catagen: 2 to 3 (then, repeat the chosen description) Increased telogen: 1 to 2 (then, repeat the chosen description) |
Follicles in telogen | Dilated infundibular unit associated to fibrotic tissue at the level of the papillary dermis |
Fibrous tracts or streamers | Pale, ill defined, sometimes compact fibers at the level of the superficial dermis |
Abbreviations: AAI, alopecia areata incognita; HP, histopathology; RCM, Reflectance confocal microscopy.