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Collagenase inhibition properties of the crude ethanol extract (E) of H. itama propolis from the involucrum of H4 and its solvent fractions (H) and (W), epigallocatechin gallate (EG). (EG) at various concentrations (0–200 μg/mL), compared with the negative control, Statistical analysis was performed using One-way ANOVA followed by Dunnett's test, with significance levels denoted as ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 for comparisons against the positive control (EG).
