Table 2.

Selection Criterion

PICOS	Inclusion	Exclusion
Population	Adult female patients with unilateral or bilateral mastectomy	Cadaver, animal
Intervention	Unilateral and bilateral DIEP flap	Other types of flap reconstructions such as TRAM flaps, latissimus dorsi flaps, or implant-based reconstructions
Comparator	Unilateral DIEP flap compared with bilateral DIEP flap
Outcomes	Primary outcome is a complete flap loss rate	Studies that do not report the primary outcome
Studies	Prospective, retrospective, comparative studies	Case reports, case series, abstracts only, letters, reviews, comments