Supplemental Fig.2. Cumulative incidence of the composite event and mortality stratified by SPP and ABI tertiles in patients with normal ABI and SPP.

The cut-off points are 71 and 83 mmHg for SPP and 1.06 and 1.18 for ABI. In 215 patients with normal ABI levels, the cumulative incidences for the composite events during 5 years were 0.63, 0.40, and 0.41 with p=0.002 (A), and those for death were 0.45, 0.25, and 0.24 with p=0.025 for SPP T1, T2, and T3, respectively (B). In 230 patients with normal SPP levels, those for composite events were 0.62, 0.47, and 0.41 with p=0.041 (C), and those for death were 0.35, 0.31, and 0.32 with p=0.866 for ABI T1, T2, and T3, respectively (D).

SPP, skin perfusion pressure; ABI, ankle-brachial index; AVEs, atherosclerotic vascular events; T1, 1st tertile; T2, 2nd tertile; T3, 3rd tertile.