Table 5.
The combined effect of CDAI and eczema on the odds of depression in subgroups.
| Subgroups | Outcome/Total | Unadjusted | Model 1 | ||
|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||
| Gender = Female | n = 98/1752 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 13/303 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 72/1326 | 2.12 (0.89–5.07) | 0.117 | 1.94 (0.74–5.05) | 0.248 |
| Eczema = Yes and CDAI=High | n = 1/26 | 0.94 (0.12–7.57) | 0.954 | 1.80 (0.25–12.70) | 0.588 |
| Eczema = Yes and CDAI = Low | n = 12/97 | 5.37 (2.14–13.46) | 0.004 | 6.06 (2.28–16.13) | 0.023 |
| P for trend | 0.003 | P for trend | 0.022 | ||
| RERI | 3.31 (−1.42–8.05) | 3.33 (−3.09–9.74) | |||
| AP | 0.62 (0.09–1.15) | 0.55 (−0.17–1.27) | |||
| SI | 4.13 (0.31–54.29) | 2.92 (0.27–32.13) | |||
| Gender = Male | n = 76/1650 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 14/485 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 52/1076 | 2.30 (1.24–4.29) | 0.022 | 1.85 (0.93–3.72) | 0.157 |
| Eczema = Yes and CDAI=High | n = 3/37 | 1.95 (0.72–5.24) | 0.213 | 2.42 (0.91–6.41) | 0.151 |
| Eczema = Yes and CDAI = Low | n = 7/52 | 8.35 (3.48–20.02) | <0.001 | 9.61 (3.36–27.52) | 0.013 |
| P for trend | <0.001 | P for trend | 0.014 | ||
| RERI | 5.10 (−1.24–11.45) | 6.34 (−3.11–15.79) | |||
| AP | 0.61 (0.27–0.95) | 0.66 (0.27–1.05) | |||
| SI | 3.27 (1.03–10.34) | 3.79 (0.89–16.09) | |||
| BMI < 25 | n = 51/1024 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 9/231 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 36/718 | 1.95 (0.80–4.76) | 0.167 | 1.75 (0.73–4.21) | 0.276 |
| Eczema = Yes and CDAI=High | n = 1/22 | 0.92 (0.13–6.64) | 0.934 | 1.36 (0.18–10.43) | 0.784 |
| Eczema = Yes and CDAI = Low | n = 5/53 | 5.77 (2.20–15.14) | 0.004 | 6.41 (2.34–17.55) | 0.022 |
| P for trend | 0.005 | P for trend | 0.023 | ||
| RERI | 3.90 (−1.37–9.17) | 4.30 (−1.72–10.32) | |||
| AP | 0.68 (0.21–1.14) | 0.67 (0.18–1.16) | |||
| SI | 5.48 (0.29–102.92) | 4.87 (0.32–74.43) | |||
| BMI ≥ 25 | n = 123/2378 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 18/557 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 88/1684 | 2.36 (1.32–4.20) | 0.013 | 1.85 (0.97–3.53) | 0.135 |
| Eczema = Yes and CDAI=High | n = 3/41 | 1.95 (0.76–5.01) | 0.192 | 2.45 (0.94–6.36) | 0.140 |
| Eczema = Yes and CDAI = Low | n = 14/96 | 6.65 (3.21–13.75) | <0.001 | 7.54 (3.58–15.88) | 0.006 |
| P for trend | <0.001 | P for trend | 0.007 | ||
| RERI | 3.34 (−1.76–8.45) | 4.24 (−1.94–10.42) | |||
| AP | 0.50 (0.00–1.00) | 0.56 (0.06–1.07) | |||
| SI | 2.45 (0.64–9.45) | 2.84 (0.61–13.24) | |||
| Smoking = No | n = 64/1808 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 10/412 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 46/1282 | 2.10 (0.91–4.83) | 0.107 | 1.77 (0.72–4.35) | 0.268 |
| Eczema = Yes and CDAI=High | n = 1/34 | 1.29 (0.16–10.34) | 0.816 | 1.53 (0.18–12.78) | 0.709 |
| Eczema = Yes and CDAI = Low | n = 7/80 | 7.46 (2.40–23.17) | 0.005 | 9.93 (2.88–34.25) | 0.015 |
| P for trend | 0.003 | P for trend | 0.014 | ||
| RERI | 5.07 (−2.81–12.95) | 7.63 (−3.71–18.96) | |||
| AP | 0.68 (0.18–1.18) | 0.77 (0.36–1.17) | |||
| SI | 4.66 (0.37–58.12) | 6.85 (0.36–131.66) | |||
| Smoking = Yes | n = 110/1594 | ||||
| CDAI and Eczema | |||||
| Eczema = No and CDAI=High | n = 17/376 | Ref | Ref | ||
| Eczema = No and CDAI = Low | n = 78/1120 | 2.36 (1.27–4.36) | 0.018 | 1.87 (1.01–3.44) | 0.103 |
| Eczema = Yes and CDAI=High | n = 3/29 | 1.64 (0.66–4.03) | 0.305 | 2.51 (1.13–5.57) | 0.073 |
| Eczema = Yes and CDAI = Low | n = 12/69 | 6.33 (3.31–12.10) | <0.001 | 6.62 (3.82–11.46) | 0.001 |
| P for trend | <0.001 | P for trend | 0.001 | ||
| RERI | 3.33 (0.17–6.49) | 3.24 (−0.31–6.79) | |||
| AP | 0.53 (0.22–0.84) | 0.49 (0.12–0.86) | |||
| SI | 2.67 (1.02–7.00) | 2.37 (0.88–6.38) | |||
OR, hazard ratio; CI, confidence intervals; Ref, reference; CDAI, composite dietary antioxidant index; Model 1 adjusting race, PIR, marriage, education, sleep duration, smoking, house smoker, hypertension, diabetes, CVD, and serum Vitamin D.