Table 2.
The production of antigen-specific IgG, IgG1, and IgG2c induced by LT33.
| Groups | Antibody titers | ||||
|---|---|---|---|---|---|
| IgG | IgG1 | IgG2c | IgG2c/IgG1 | ||
| PBS | – | – | – | – | |
| BCG | – | – | – | – | |
| Anti-ESAT-6 | ESAT6 | 3.54 ± 0.43 | 4.22 ± 0.14 | 4.45 ± 0.03 | 1.055 |
| LT33 | 3.10 ± 0.05 | 4.15 ± 0.11 | 4.24 ± 0.09 | 1.022 | |
At 12 weeks after the last immunization, the IgG, IgG1, and IgG2c against ESAT6 in serum were measured by ELISA. Data are expressed as means ± standard deviation (SD) (n = 3). Antibody titers are presented as the means of log10 antibody titers ± SD.