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. 2024 Nov 22;14:1453346. doi: 10.3389/fonc.2024.1453346

Table 1.

The clinicopathologic characteristics of all patients.

  Normal renal function(n =645) Preoperative renal insufficiency(n =60 ) p
Male 553 (85.7%) 54 (90.0%) 0.361
Age 67 (58-73) 69 (60-76) 0.067
ORC 451 (69.9%) 41 (68.3%) 0.798
LRC 194 (30.1%) 19 (31.7%)  
BMI (kg/m2) 23.9 (21.8-26.3) 24.3 (22.2-26.0) 0.443
ASA score <0.001
≤2 552 (85.6%) 398(63.3%)  
>2 93(14.4%) 22(36.7)  
Type of urinary diversion     0.014
Ureterocutaneostomy 166 (25.7%) 26 (43.3%)  
Ileal conduit 447 (69.3%) 33 (55.0%)  
Orthotopic neobladder 32 (5%) 1 (1.7%)  
Time of operation (min) 302 (230-374) 269 (209-354) 0.07
EBL (ml) 500(200-1000) 600 (200-1000) 0.785
Clavien-Dindo class     0.001
0 190 (29.5%) 14(23.3%)  
1 7(1.1%) 0  
2 424 (65.7%) 36 (60.0%)  
3 17 (2.6%) 4 (6.7%)  
4 6 (0.9%) 5 (8.3%)  
5 1 (0.2%) 1 (1.7%)  
Major complication 24 (3.7%) 10 (16.7%) <0.001
Postoperative stay (days) 10 (8-14) 11 (8-15) 0.938
Clinical T stage     <0.001
Ta and Tis and T1 194 (30.1%) 5 (8.3%)  
T2 226(35.0%) 16 (26.7%)  
T3 142 (22.0%) 20 (33.3%)  
T4 83 (12.9%) 19 (31.7%)  
Pathological T stage     <0.001
Ta and Tis and T1 189 (29.3%) 5 (8.3%)  
T2 204 (31.6%) 15 (25.0%)  
T3 195(30.2%) 30 (50.0%)  
T4 57(8.8%) 10 (16.7%)  
Pathologic nodal stage 0.027
N0 553(85.7%) 45(75%)  
N+ 92(14.3%) 15(25%)  
Pathologic grade     0.613
Low grade 67 (10.4%) 5 (8.3%)
High grade 577 (89.6%) 55 (91.7%)  
Negative margin 635 (98.4%) 56(93.3%) 0.026
Positive margin 10 (1.6%) 4 (6.7%)  
Chemotherapy 126 (19.5%) 9 (15.0%) 0.393
No chemotherapy 519 (80.5%) 51 (85.0%)  

ORC, open radical cystectomy; LRC , laparoscopic radical cystectomy; BMI, Body Mass Index; EBL, estimated blood loss; ASA, American Society of Anesthesiologists.