Table 5.
Number of patients with relapse and death, DFS, and OS times according to molecular subtypes for FOXP3 and MVD categories.
| Molecular subtypes | DFS, n* (median)* | p-value | DFS, n(median) | p-value | ||
|---|---|---|---|---|---|---|
| Low FOXP3 | High FOXP3 | Low MVD | High MVD | |||
| Luminal A | 0/33 (NE)** | 1/32 (NE) | NE | 0/31 (NE) | 1/34 (NE) | NE |
| Luminal B (HER2-) | 3/42 (NE) | 7/39 (NE) | 0.17 | 8/37 (NE) | 2/44 (NE) | 0.02 |
| Luminal B (HER2+) | 2/6 (NE) | 1/13 (NE) | 0.08 | 3/15 (NE) | 0/4 (NE) | 0.36 |
| HR- HER2+ | 1/4 (NE) | 0/3 (NE) | 0.38 | 0/3 (NE) | 1/4 (NE) | 0.39 |
| HR- HER2- | 1/4 (NE) | 1/11 (NE) | 0.43 | 1/9 (NE) | 1/6 (NE) | 0.43 |
| Overall | 7/89 (NE) | 10/98 (143.5) | 0.61 | 12/95 (NE) | 5/92 (NE) | 0.07 |
| Molecular subtypes | OS, n(median) | OS, n(median) | p-value | |||
| Low FOXP3 | High FOXP3 | Low MVD | High MVD | |||
| Luminal A | NE | NE | 0.59 | NE | NE | 0.80 |
| Luminal B (HER2-) | NE | NE | 0.55 | NE | NE | 0.11 |
| Luminal B (HER2+) | NE | NE | 0.49 | NE | NE | 0.54 |
| HR- HER2+ | NE | NE | 0.58 | NE | NE | 0.30 |
| HR- HER2- | NE | NE | 0.48 | NE | NE | 0.15 |
| Overall | NE | NE | 0.59 | NE | NE | 0.85 |
* n is presented as relapse/total number of patients. Median values are presented in months **NE; not estimated.