Table 2. The changes in lung function and ACT score at the 3-month follow-up.

Variable	Low IgE ACO (n = 22)	High IgE ACO (n = 60)	P value	Atopy (−) ACO (n = 60)	Atopy (+) ACO (n = 47)	P value	Low blood eosinophil ACO (n = 62)	High blood eosinophil ACO (n = 116)	P value	Low sputum eosinophil ACO (n = 25)	High sputum eosinophil ACO (n = 37)	P value
ΔFEV1 (mL)	−0.2 ± 0.5	−0.3 ± 0.5	0.467	−0.4 ± 0.6	−0.5 ± 0.5	0.589	−0.3 ± 0.6	−0.3 ± 0.5	0.583	−0.3 ± 0.3	−0.3 ± 0.3	0.995
ΔFEV1 (%)	−4.4 ± 9.2	−11.4 ± 16.7	0.023	−11.9 ± 18.0	−13.5 ± 15.8	0.628	−11.0 ± 17.3	−9.5 ± 14.9	0.549	−8.4 ± 13.1	−11.4 ± 11.2	0.488
ΔFEV1/FVC	−4.8 ± 12.0	−6.1 ± 12.9	0.682	−7.2 ± 9.6	−6.1 ± 10.5	0.578	−5.5 ± 11.5	−5.3 ± 10.3	0.885	−0.4 ± 6.4	−4.9 ± 6.3	0.049
ΔACT	−0.8 ± 1.0	−0.2 ± 5.3	0.685	−1.3 ± 5.3	−0.6 ± 4.5	0.757	−1.8 ± 6.3	−1.1 ± 3.6	0.654	−3.3 ± 4.5	−5.0 ± 10.4	0.809

The changes (Δ) were calculated by 3 months to baseline. P value was calculated with Student’s t-test for continuous variables. Bold-styled values denote significant ones.

ACT, asthma control test; IgE, immunoglobulin E; ACO, asthma–chronic obstructive pulmonary disease overlap; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity.