Fig. 5.

The model of the hedgehog CoV RBD model (light green) was superimposed onto the crystal structure of MERS-CoV RBD (pink) complexed with human DPP4 (beige) (PDB ID 4L72). The residues of MERS-CoV RBD known to contact with DPP4 are colored yellow (d < 3.6 Å). The β5-β6 linking loop of the MERS-CoV RBD is indicated with a red arrow and the β6-β7 linking loop is indicated with a black arrow. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)