2. Levels of quality of a body of evidence in the GRADE approach.
Underlying methodology | Quality rating |
Randomised trials; or double‐upgraded observational studies. | High |
Downgraded randomised trials; or upgraded observational studies. | Moderate |
Double‐downgraded randomised trials; or observational studies. | Low |
Triple‐downgraded randomised trials; or downgraded observational studies; or case series/case reports. | Very low |