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. 2010 Oct 6;2010(10):CD008505. doi: 10.1002/14651858.CD008505.pub2

2. Levels of quality of a body of evidence in the GRADE approach.

Underlying methodology Quality rating
Randomised trials; or double‐upgraded observational studies. High
Downgraded randomised trials; or upgraded observational studies. Moderate
Double‐downgraded randomised trials; or observational studies. Low
Triple‐downgraded randomised trials; or downgraded observational studies; or case series/case reports. Very low