TABLE 1.
Demographic and clinical characteristics | Value |
---|---|
Demographics | |
Sex female, n (%) | 120 (54.5) |
Median age at first MG symptom, years (P25–P75) | 60.5 (44.3–73.0) |
Median age at first visit, years (P25–P75) | 70.0 (56–83) |
Clinical characteristics | |
Time from first symptom to diagnosis, months (SD) | 8.8 (21.3) |
Time from baseline visit to diagnosis, days a (SD) | 48 (132.0) |
Autoimmunity, n (%) b | |
Anti‐AChR | 186 (84.5) |
Anti‐MuSK | 13 (5.9) |
Seronegative | 22 (10.0) |
Baseline MGFA clinical classification, n (%) | |
I | 77 (35.0) |
IIA | 48 (21.8) |
IIB | 58 (26.4) |
IIIA | 7 (3.2) |
IIIB | 17 (7.7) |
IVA | 1 (0.5) |
IVB | 9 (4.1) |
V | 3 (1.4) |
MGFA class at maximal worsening during the study follow‐up, n (%) | |
IIA | 48 (21.8) |
IIB | 49 (22.3) |
IIIA | 34 (15.5) |
IIIB | 47 (21.4) |
IVA | 5 (2.3) |
IVB | 24 (10.9) |
V | 13 (5.9) |
Drug refractory status during study follow‐up, n (%) | 22 (10.0) |
Death during study period n, (%) | 27 (12.3) |
Abbreviations: AChR, acetylcholine receptor; MG, myasthenia gravis; MGFA, Myasthenia Gravis Foundation of America; MuSK, muscle‐specific kinase; P, percentile; SD standard deviation.
Among the 133 (60.5%) patients who were diagnosed after their first visit.
One patient was anti‐AChR‐positive and anti‐MuSK‐positive.