TABLE 1.
Descriptive statistics.
| Parameter | Patients with residence at diagnosis | Patients included with historical data | p § |
|---|---|---|---|
| Median (IQR) | Median (IQR) | ||
| Age at onset (years) | 68.2 (60.3–74.4) | 68.2 (60.2–74.3) | 0.949 |
| Onset–diagnosis interval (months) | 9.0 (5.0–13.1) | 9.0 (5.0–13.1) | 0.194 |
| ΔALSFRS‐R at diagnosis (point loss per month) | 0.649 (0.299–1.323) | 0.642 (0.290–1.323) | 0.220 |
| Survival (years) | 2.8 (1.9–4.0) | 2.3 (1.5–3.7) | 0.853 |
| n (%) | n (%) | p* | |
|---|---|---|---|
| Sex | |||
| Male | 587 (53.5) | 566 (53.4) | >0.999 |
| Female | 511 (46.5) | 494 (46.6) | |
| Site of onset | |||
| Bulbar onset | 376 (34.3) | 362 (34.1) | 0.993 |
| Spinal onset | 702 (63.9) | 678 (64.0) | |
| Respiratory onset | 20 (1.8) | 20 (1.9) | |
| Genetic mutations | |||
| Wild‐type | 816 (74.3) | 787 (74.3) | 0.987 |
| c9orf72, SOD1, TARDBP, FUS | 104 (9.5) | 103 (9.7) | |
| Not assessed | 178 (16.2) | 170 (16.0) | |
| Total | 1098 (100.0) | 1060 (100.0) |
Note: Patients with residence at diagnosis and patients with complete residential historical data were compared using Mann–Whitney U test (§) for continuous variable and chi‐square test for categorical variables (*).
Abbreviations: ALSFRS‐R, Revised Amyotrophic Lateral Sclerosis Functional Rating Scale; IQR, interquartile range.