Figure 2. Symptom severity of individuals who reported neuropathy symptom incidence.

Participants ranked severity between 2 and 5, with 5 being the most severe. (A) E2 carriers in the strength intervention experienced significantly more neuropathy symptoms than E2 non-carriers both during and after the intervention time point. ^* p = 0.012, ^*** p = 0.003, respectively. (B) During the post-intervention timepoint, the opposite pattern was noted with E4 carriers experiencing less neuropathy symptoms in the strength intervention group. ^* p = 0.014).