Table 1.

Characteristics of the included studies

Author/Ref.	Year	Journal	Country	Study population	Dose/Duration	Age group (year)	Study design
Ramesh et al.[36]	2020	J. Infect. Dis.	India	LAmB + MIL=16 MIL=16	3 injections of LAmB, 5 mg/kg + MIL100 mg/day (45 days) 100mg/day (for 90 days)	9-60	Cohort study
Pandey et al.[37]	2017	Br. J. Dermatol.	India	MF + PM=30	2.5mg/kg + 11mg/kg for 30 days	5-65	RCT
Abongomera et al.[40]	2016	PLOS One	Sudan	SSG + PM=77	20 mg/kg/day + 11mg/kgfor 17 days	≥5	Retrospective observational study
Younis et al.[41]	2015	Int J Res Med Sci.	Sudan	SSG + PM=9	20mg/kg + 11mg/base/kg/day for 30 days	5-17	Case series
Ramesh et al.[38]	2014	Acta DermVenereol	India	AmB + MIL=3	50 mg AmB for 20 days + 50 mg oral MIL thrice daily for 40 days	Case1=20 Case2=24 Case3=26	Case report
Ramesh et al.[42]	2010	Indian J Dermatol Venereol Leprol	India	Group I SSG=32 Group II SSG + ALP=10 SSG + RMF=6 SSG + ALP + RMF=5 SSG + MW vaccine=8	20 mg/kg/day (total dose 1 gm) 20 mg/kg/day (total dose 1 gm) + 800 mg/day 20 mg/kg/day (total dose 1 gm) + 15 mg/kg varied from 750-900 mg/day. 20 mg/kg/day (total dose 1 gm) + 800 mg/day + 15 mg/kg varied from 750-900 mg/day. 20 mg/kg/day (total dose 1 gm) + 0.1 ml	18-65	Retrospective study observational study
Musa et al.[43]	2008	Trans R Soc Trop Med Hyg	Sudan	ALM + BCG + SSG=15 Placebo + SSG=15(control)	100 mcg + one-tenth of the 0.1 ml of dose used in TB for 4 weekly doses + 20 mg/kg/day for 40 days 20mg/kg for 40 days	7-60	RCT
Sharma et al.[39]	2007	Indian J Dermatol VenereolLeprol	India	SSG + RMF=8	10mg/kg/day + 900mg/daily for 120 days	18-39	Cohort study
Khalil et al.[44]	1996	Trans R Soc Trop Med Hyg	Sudan	TRF + ITZ=9	250 mg/day + 200 mg/day for 4 weeks	>18	Cohort study

MIL-miltefosine, PM-paramomycin, TRF-terbinafine, ITZ-itraconazole, ALM-alum-precipitatedautoclaved Leishmaniamajorvaccine, BCG-Bacille Calmette-Guerin, SSG-sodium stibogluconate, RMF-rifampicin, LAmB-liposomal amphotericin-B, AmB-amphotericin-B, ALP- Allopurinol, RCT-Randomized controlled trial