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. 2024 Dec 6;19(12):e0312800. doi: 10.1371/journal.pone.0312800

Fig 4. Effect of nsp5 T25I mutation on SARS-CoV-2 proliferation in mouse lung tissue.

Fig 4

(A) Schematic of the infection experiments. Changes in body weight after virus inoculation. Day 3 after inoculation, n = 3 (B). Day 4 after infection, n = 5 (D). Expression of the viral N gene in mouse lung tissues. Day 3 after inoculation, Values represent means ± SD of three samples. (C). Day 4 after infection, Values represent means ± SD of five samples. (E). ns, no statistically significant difference; d.p.i., days post-infection.*P < 0.05, ***P < 0.001, and #P < 0.0001.