Table 4.

The table shows different applications of Frexalimab for possibly treating various autoimmune diseases, along with its mechanism of action for each particular disease and the current status of Frexalimab with regard for being a candidate drug for treating these diseases

Condition	ClinicalTrials.gov ID	Use	Mechanism of action	Current status
Sjögren’s Syndrome	NCT04572841	Potential use in reducing inflammation and improving glandular function	Inhibits specific immune cells, reducing inflammation and tissue damage	Investigational, clinical trials ongoing
Diabetes	NCT06111586	Exploring the potential to improve glycemic control and reduce immune-mediated beta cell destruction	Modulates immune response, potentially preserving pancreatic function	Preclinical/early clinical studies
Systemic lupus erythematosus (SLE)	NCT05039840	Potential use in reducing disease activity and preventing organ damage	Targets immune pathways involved in lupus pathology	Clinical trials ongoing